Knowledge about "Natural Human Ceramide"
The world's first "natural human ceramide"
As introduced earlier, the Genuin R&D has successfully purified human ceramide from natural materials for the first time in the world.
Until now, natural ceramides used in cosmetics and other products were extracted from natural plant and animal materials such as konnyaku, horse, and corn, but they were not "human-type''.
Also, what was called "human ceramide" was a synthetic human ceramide, and the only one available was chemically synthesized from yeast.
The "natural human ceramide" that have created by the Genuine R&D is the world's first ceramide that is purified from natural brewing fermentation lees rather than chemicals.
Naturally occurring ceramide-related substances (sphingolipids)
Commercially available ceramide-related substances (excluding reagents)
Characteristics of natural human ceramide (human ceramide NP/AP)
・The first natural ceramide that can be stably supplied
・Humanized ceramide without cis isomer and L-isomer
・99% purity products that can be used as reagents are also available
・Can also be supplied as a mixture with glucosylceramide and sterol glycosides
・Cosmetic material with high barrier function improvement effect
・Atopic dermatitis treatment drug
・Safe and effective as a food material
*Human ceramide NP: N-tetradecanoyl phytosphingosine
*Human ceramide AP: N-α-tetradecanoyl phytosphingosine
Strengthens skin's natural moisturizing and barrier functions.
The outermost layer of the skin, which is the largest tissue in the human body, is the stratum corneum. A component called "intercellular lipid" plays the role of connecting the keratinocytes that make up the stratum corneum, and ceramide accounts for 50% of this intercellular lipid.
However, this ceramide decreases with age, making it difficult for the skin to retain sufficient moisture, and as we age, the skin's natural moisturizing and barrier functions are lost.
It is important to compensate for the decrease in ceramide by using external ceramide.
Human-type ultra-long chain free ceramide
Human-type ceramide refers to one of the nine types of free ceramide present in the stratum corneum of the skin. It does not have polar groups such as sugars, and its stereoisomers are D and trans.
The natural human ceramide produced by Genuin R&D has a large carbon number of 24 and is an extremely long chain. Natural human ceramide is characterized by its high moisturizing power compared to plant ceramide and synthetic human ceramide.
Ceramides with short molecules easily lose moisture and cannot exert sufficient moisturizing effects. Our natural human-type ceramide has long molecules and can stably retain moisture.